Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution

[caption id="attachment_48319" align="alignright" width="195"] Human Longevity Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution[/caption] by Raymond C. Valentine (Author), David L. Valentine (Author) More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman’s famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington’s disease, Parkinson’s disease, and traumatic brain disease in animal models of neurodegeneration. This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity. Product Details Hardcover: 259 pages Publisher: CRC Press; 1 edition (September 18, 2014) Language: English ISBN-10: 1466594861 ISBN-13: 978-1466594869