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9783031123894
Springer
2022
English
1791
22 MB
By Cara-Lynne Schengrund, Robert K. Yu This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators. Product Details Publisher : Springer; 2nd ed. 2023 edition (October 19, 2022) Language : English Hardcover : 513 pages ISBN-10 : 3031123891 ISBN-13 : 978-3031123894
