Drug Selectivity: An Evolving Concept in Medicinal Chemistry (Methods and Principles in Medicinal Chemistry) (PDF)

by Norbert Handler (Editor),‎ Helmut Buschmann (Series Editor),‎ Raimund Mannhold (Series Editor),‎ Jörg Holenz (Series Editor) & 1 more_0 The book provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist. Product Details Series: Methods and Principles in Medicinal Chemistry Hardcover: 536 pages Publisher: Wiley-VCH; 1 edition (February 27, 2018) Language: English ISBN-10: 3527335382 ISBN-13: 978-3527335381 Product Dimensions: 6.7 x 6.7 x 9.4 inches