Biology and Treatment of Leukemia and Bone Marrow Neoplasms

By Vinod Pullarkat, Guido Marcucci This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students. Product Details Publisher ‏ : ‎ Springer; 1st ed. 2021 edition (October 10, 2021) Language ‏ : ‎ English Hardcover ‏ : ‎ 204 pages ISBN-10 ‏ : ‎ 3030783103 ISBN-13 ‏ : ‎ 978-3030783105 ISBN-13 ‏ : ‎ 9783030783105 eText ISBN: 9783030783112