Basics and Clinical Applications of Drug Disposition in Special Populations

Basics and Clinical Applications of Drug Disposition in Special Populations provides an up-to-date, authoritative exploration of predicting and managing drug disposition across diverse patient groups, including pediatric, geriatric, obese, and those with renal or hepatic impairments. The book emphasizes the use of pharmacokinetic models to account for variability between populations and optimize drug dosing. Written by a team of leading experts, the text combines theoretical insights with practical applications to guide clinicians, pharmacologists, and researchers in delivering safe and effective pharmacotherapy to special populations.

Key Features:

• Comprehensive coverage of drug disposition in pediatrics, geriatrics, obesity, renal insufficiency, and hepatic insufficiency.
• Emphasis on pharmacokinetic modeling to predict inter-population variability and optimize dosing regimens.
• Includes discussions on regulatory considerations and clinical research in special populations.
• Explores model-based pharmacokinetic approaches and practical applications in drug development.
• Addresses cutting-edge topics, including artificial intelligence in drug discovery and development.
• Written by recognized experts, offering evidence-based guidance for clinical and research settings.